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Objective@#To explore the association of the frequency of domestic violence witness in childhood with the quality of life (QOL) of college students, and to provide a reference for improving the quality of life of students who domestic violence witness in childhood.@*Methods@#In October 2018, a total of 4 034 college students from four universities in Hefei, Anhui Province, were selected to participate in this study. The Conflict Tactics Scales Short Form (CTS2SF) and the World Health Organization Quality of Life-Brief (WHOQOL-BREF) were used to assess the effect of witnessing domestic violence in childhood on the QOL of college students. Multiple linear regression was used to analyze the relationship between the different frequencies of witnessing domestic violence in childhood and the QOL of college students.@*Results@#The mean scores of the subjective assessment of QOL, health subjective assessment, physiology, psychology, social relationships, and environment were (14.06±3.25) (13.42±3.47) (12.61±2.02) (14.09±2.62) (13.72±2.71) (13.77±2.46), respectively. The multiple linear regression model showed that, witnessing domestic violence in childhood was negatively correlated with the QOL of college students (P<0.01). Although occasional expose to severe family violence in childhood was not associated with the health subjective assessment and the environmental dimensions, the different frequencies of witnessing domestic violence in childhood were negatively correlated with the QOL of college students (P<0.05).@*Conclusion@#Frequency of domestic violence witness in childhood is associated with the mean scores of the QOL of college students. It is necessary to explore effective prevention and intervention programs for exposure to domestic violence in childhood.
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Abstract?AIM: To assess the current situation of trachoma in Shaanxi Province and analyze its epidemiology and clinical features.?METHODS: The World Health Organization ( WHO ) simplified trachoma grading system was used for the recognition and registration of cases of trachoma. Trachoma rapid assessment ( TRA ) was conducted and 30.3687 million people from Shaanxi province were screened. Eyelids, eyelashes, conjunctiva and cornea were examined.The prevalence of trachoma trichiasis ( TT) in Shaanxi Province was estimated.?RESULTS: Totally 987 cases with TT were collected in Shaanxi province, in which 395 cases were male and 592 cases were female. The overall TT prevalence was 0.0325‰.The age of TT cases ranged from 25-86 years old, and concentrated in the 60-80 years old, only 58 cases were <50 years old.There were 12 cases of TT combined corneal opacity (CO) and the ratio was 1.2%. Sixty-four patients were cured by electrolysis trichiasis, the remaining 923 patients corrected by surgery interventions.?CONCLUSION: Based on the results of this study, trachoma blind is no longer estimated as a public health problem in Shaanxi province, as the detection rate of TT was less than 1‰ which is the goal of “elimination of trachoma” worldwide.
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AlM: To explore the visual evoked potential in infantile orbital cellulitis' clinical applications by monitoring the visual evoked potential changes in infantile orbital cellulitis before, during and after treatment. METHODS:Twenty-three cases of CT diagnosed single orbital cellulitis were examined by the visual evoked potentials. The affected eyes as observation group, and healthy eyes as control group. Comparative observation of visual evoked potential changes in amplitude and incubation period before, during and after the treatment. RESULTS: Compared with the control group, the observation group's visual evoked potential changes included reduced amplitude, extended incubation period. With the treatment progress, the observation group had gradual increase in amplitude, gradual reduction in incubation period. CONCLUSlON: ln infantile orbital cellulitis, the use of visual evoked potentials is a simple, feasible and effective method to monitoring the visual function during the treatment.
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<p><b>OBJECTIVE</b>To study the mutation of FRMD7 gene in a Chinese family with congenital idiopathic nystagmus.</p><p><b>METHODS</b>Forty-six individuals in the Chinese family with congenital idiopathic nystagmus, including 16 patients, 19 normal siblings and 11 spouses, were investigated under informed consent. Genomic DNA of all 46 members was isolated by standard protocol. The X-linked inherited pattern was ascertained by investigating the history of the family members and the clinical feature of each individual. The genome scan on X chromosome was performed after PCR amplification for microsatellite markers. LOD scores were calculated with Linkage 5.1. Direct DNA sequence analysis was carried out to find the gene mutation responsible for the disease.</p><p><b>RESULTS</b>A maximum LOD score of 8.55 (theta=0) was obtained with polymorphic marker DXS1047. Haplotype construction of the family defined the disease interval between DXS8059 and DXS8033. Direct DNA sequence analysis revealed a heterozygous mutation of G990T in exon 9 of the FRMD7 gene in all patients, which was not present in unaffected family members.</p><p><b>CONCLUSION</b>Congenital nystagmus is a clinically and genetically heterogeneous ocular movement disease. The mutation of G990T of the FRMD7 gene is the underlying molecular pathogenesis for this family with congenital nystagmus.</p>